Articles by Seirots
Mitragyna speciosa Kratom is illegal in many South-East Asian countries, such as Thailand, Malaysia, Myanmar (Burma) and Vietnam (though the specificities of the law is unclear).
Kratom use is, however still quite common in these countries, especially in rural areas, even though these countries...
“Withdrawals” or “withdrawal symptoms”, also known as
withdrawal/abstinence syndrome, refers to a series of characteristic signs and symptoms that appear when a drug is regularly used for a long time and then suddenly discontinued or decreased in dosage.
Withdrawal is connected to forms of...
The concept of "drug tolerance”, refers to the gradual decrease of a subject’s reaction and sensitivity to a psychoactive substance or drug, implying that progressively larger doses are required to achieve the desired effect.
Drug tolerance can involve both psychological drug tolerance as well...
The term “Opioids” is a blanket term used for any drug, including opiates, which are active by binding to the C.N.S. or gastrointestinal tract opioid receptors, thus having an action comparable to that of opiates.
It is a broad class of narcotics whose activity comes from their receptor...
Selected bibliography on Mitragyna speciosa Kratom and Kratom alkaloids
Amattayakul T., The kraton leaves. J. Department of Medical Sciences, Thailand, vol. 2: 2, 104-108, 1960.
Atthakor P. "Role Seen For Traditional Herbal Stimulant": Bangkok Post November 27, 1999
Carbonin PU, Greco A...
Though Mitragyna speciosa Kratom has been used for a long time in South-East Asia, it does not enjoy a rich, often romanticized history similar to that of other drugs such as opium or cannabis.
Kratom culture and use was, until recently restricted to South-Eastern Asia, where it was used...
As previously explained in the section “Pharmacology and mode of action of Mitragyna speciosa Kratom” as well as in the “Potential applications and modern uses of Mitragyna speciosa Kratom” section, Mitragyna speciosa Kratom actually has a strong potential as a substance to help with the...
Mitragyna speciosa Kratom use is legal in most parts of the world, and is not specifically tested for in drug-screens or drug tests. Yet Kratom users facing potential drug-tests, such as urine drug-screens, which are very common in the U.S.A. for instance- should be very careful with Kratom use...
As previously mentioned, despite Mitragyna speciosa Kratom’s relatively long history of human use, Kratom and Kratom use has rarely been studied extensively, even in countries where Kratom use is traditional.
Such a country, Thailand, actually banned Kratom in 1943 (a ban which is now under...
A few Kratom users, those more sensitive than others, have had allergy-like reactions to Mitragyna speciosa Kratom, especially in higher doses, which causes them to feel a generalised body itching, similar to opioids. This unpleasant sensation is most likely due to histamine output, and can be...
Mitragyna speciosa Kratom use appears to be very safe in standard recreational doses.
A person who consumes too much Mitragyna speciosa Kratom will experience strong nausea and vomit the consumed Kratom before their body would absorb enough alkaloids to cause a potentially dangerous overdose...
Can Mitragyna speciosa Kratom be combined safely with other substances?
In general, drug combination can be hazardous, problematic and risky, and one has to be careful of potentially negative or dangerous pharmaceutical interactions. One should proceed with caution, and with lower doses of both...
Some combinations may actually potentiate the effects of Mitragyna speciosa Kratom, which is something to be aware of when experimenting with Kratom.
Most of these Kratom potentiators are actually similar to those that work for opioids and opiates, since they act on similar receptors in similar...
Typical Mitragyna speciosa Kratom doses can vary greatly, depending on such factors as potency of the Kratom, tolerance of the user and personal metabolism / response.
It is rather clear that Kratom’s stimulant and sedative effects work in tandem. Yet with regular use, a tolerance develops to...
What is clear is that Mitragyna speciosa Kratom is not recommended for daily use.
While such a practice is not nearly as problematic or dangerous as it would be with opiate or opioid use, it is clear that it is with regular use that most of Mitragyna speciosa Kratom’s side effects and health...
Mitragyna speciosa Kratom has been used as a medicine and as a recreational psychoactive for a long time in South-East Asia, and is therefore known to be relatively safe. Yet it is important to note that Kratom’s action and eventual side effects are not yet fully understood or documented, and...
Mitragyna speciosa Kratom leaf, Kratom leaf powder and extracts are best preserved in an cool environment where they are not exposed to air, humidity, heat or U.V. light.
One could say that the storing conditions of Kratom are similar to those that one would use for good tea leaves. An airtight...
Mitragyna speciosa Kratom products can be brewed into tea or drinks, but leaves and leaf powder can also be swallowed directly, and still be active, which makes “cooking” with Kratom a real possibility- though one should keep in mind that these ideas or recipes actually aim at masking the...
Extraction of the Mitragyna speciosa Kratom alkaloids into the tea is show to be facilitated by using powdered material, as this increases the surface area. So if one has crushed or whole dried Kratom leaf, it is best to grind the leaf to a rough powder in a food processor or a coffee grinder...
Kratom can be smoked, but this is less recommended, as it is less effective than oral consumption, and slightly more complex.
Indeed, the amount of leaf that constitutes a typical Kratom dose is too large to be smoked easily. This implies that smoking Kratom products has little real advantage...