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  1. Seirots

    Mitragyna speciosa Kratom tea and Kratom leaves infusions

    In South-East Asia Mitragyna speciosa Kratom leaf is also often made into a tea. This has also become, by far, the most common and popular method using Kratom outside of Asia. Mitragyna speciosa Kratom leaves are usually boiled, strained and drunk. Some people like to mix Kratom tea with some...
  2. Seirots

    Eating / swallowing dried Mitragyna speciosa Kratom leaves and Kratom leaf powder

    This is a very simple and efficient way of consuming Mitragyna speciosa Kratom. The simplest way would be the “toss and wash”, placing the Kratom leaf or Kratom leaf powder in a glass of water, stirring and then gulping down the glass of water followed by another one. Mitragyna speciosa Kratom...
  3. Seirots

    Mitragyna speciosa Kratom extracts

    A paste-like concentrated Kratom extract can be prepared by boiling of a quantity of fresh or dried Mitragyna speciosa Kratom leaves, which is then lengthily evaporated by boiling down, until the liquid is reduced to a concentrated tar / resin like extract, which can be stored for later use...
  4. Seirots

    Chewing Mitragyna speciosa Kratom leaves

    In South-East Asia, and Thailand in particular, Mitragyna speciosa Kratom is most often chewed fresh, in whole leaf form, usually after removing the leaves’ central vein, which helps chewing and is said to prevent nausea. This method of using Kratom is by far the most common, but is also...
  5. Seirots

    How does one prepare and use Mitragyna speciosa Kratom ?

    There are multiple ways to prepare Mitragyna speciosa Kratom, from making a simple tea with the leaves, leaf powder or extract, to more complex preparations, such as “Kratom cooking”. More than the novelty aspect, these preparations’ aim is to help mask or diminish the taste and bitterness of...
  6. Seirots

    Recreational use of Mitragyna speciosa Kratom as a relaxant

    Relatively unknown outside South-east Asia until recent times, the increased circulation of information and open medias such as the Internet, has allowed Mitragyna speciosa Kratom to be introduced to the dynamic community of users and researchers of psychoactive substances. Mitragyna speciosa...
  7. Seirots

    Use of Mitragyna speciosa Kratom as an immuno-stimulant, immune system booster

    Mitragyna speciosa Kratom shares some pharmacological properties with Uncaria tomentosa or (uña de gato/cat’s claw), a plant well known for its positive effects on the immune system. This has not been studied thoroughly, but traditional medical use of Mitragyna speciosa Kratom leaves, with...
  8. Seirots

    Use of Mitragyna speciosa Kratom for sexual enhancement and sensual exploration

    Finding a positive balance between Mitragyna speciosa Kratom use and sex is somewhat delicate, and very much dose related. In its traditional context of use, Mitragyna speciosa Kratom does have the reputation of being a sexual enhancer, which seems logical, since Kratom is also a stimulant, used...
  9. Seirots

    Use of Mitragyna speciosa Kratom as an opiate substitute and for opiate detoxification

    Due to its mode of action, Mitragyna speciosa Kratom could become a potential alternative to methadone, which is now commonly used in the detoxification process from opiates and opioids addiction, especially if its partial binding action on μ opioid receptors is confirmed by further research...
  10. Seirots

    Medical uses of Mitragyna speciosa Kratom

    Mitragyna speciosa leaves, with their complex and rich chemical makeup, could easily have various practical applications in modern medicine, or become source of new and useful chemicals, which could be isolated from its specific psycho-physiologically active constituents. Mitragyna speciosa...
  11. Seirots

    Forms and types Mitragyna speciosa Kratom

    The term Kratom refers to the Mitragyna speciosa tree, but also mainly to this tree’s leaves when used as a psychoactive or medicine, and their derived products such as crude extracts. The most common acceptance is that Kratom refers specifically to Mitragyna speciosa. Yet due to regional...
  12. Seirots

    Mitragyna speciosa Kratom “strains”

    With the development of Kratom trade, some Kratom “strains” or denominations have become common. These strain names were created or chosen according to a wide range of factors, such as actual geography / production area, physical appearance, or estimations of grade and potency for instance. Some...
  13. Seirots

    ”Fake Kratom”

    The Internet fuelled a globalisation of Kratom’s availability, and has also lead to some mistakes or even abuse by vendors. Fake Kratom is said to have been widely sold in the past, notably under the name "mellow gold", which was one of the first imports of what was thought to be Mitragyna...
  14. Seirots

    Common forms of Mitragyna speciosa Kratom

    The following common forms and preparations of “true” Mitragyna speciosa Kratom can be distinguished: Leaf form Kratom Traditional Kratom users of Thailand and Malaysia distinguish between different types of Kratom, the two main varieties being distinguished by the colour leaf’s veins – which...
  15. Seirots

    Mitragyna speciosa Kratom botany

    The vernacular term Kratom refers to the Mitragyna speciosa var. Korthals tree and the products derived from its leaves, which concentrate the plant’s active principles. The botanical classification of Mitragyna speciosa Kratom is as follows: Division: Magnoliophyta Class: Magnoliopsida Order...
  16. Seirots

    Mitragyna speciosa Kratom cultivation

    Recently Mitragyna speciosa Kratom has been successfully cultivated outside of its traditional / indigenous growing area, from seeds then, more frequently, from cuttings. Growing Mitragyna speciosa Kratom from seed is very difficult, and it is much more recommended to start cultivation from...
  17. Seirots

    Pharmacology and mode of action of Mitragyna speciosa Kratom

    Mitragyna speciosa Kratom is most commonly classified as a “non-opioid narcotic”, yet this classification only partially reflects the effects of Kratom, which also has notable stimulant effects. Through its phyto-chemistry, pharmacology and psycho-physiological activity, Mitragyna speciosa...
  18. Seirots

    What are Mitragyna speciosa Kratom’s main psychoactive constituents?

    The Mitragyna species are very rich in active compounds, and over 40 alkaloids have already been isolated in the leaves of its various species. Mitragyna speciosavar. Korthals has over 25 reported active alkaloids. The alkaloid content of the Kratom tree’s leaves varies from place to place, and...
  19. Seirots

    Mitragynine

    Mitragynine is an indole alkaloid with the molecular formula C23H30N2O4. It is the most abundant active alkaloid in the plant Kratom plant Mitragyna speciosa, and was therefore first thought to be responsible for the plant’s activity, before 7-hydroxymitragynine was looked into, and proved to be...
  20. Seirots

    7-hydroxymitragynine

    Mitragynine was once thought to be Mitragyna speciosa Kratom’s main active ingredient, yet more recently it has been found that the main active constituent is in fact more likely to be the potent 7-hydroxy derivative of mitragynine: 7-hydroxymitragynine First mentioned in a 1994 study paper...
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