Articles

Mitragynine was once thought to be Mitragyna speciosa Kratom’s main active ingredient, yet more recently it has been found that the main active constituent is in fact more likely to be the potent 7-hydroxy...
Though Mitragyna speciosa Kratom has been used for a long time in South-East Asia, it does not enjoy a rich, often romanticized history similar to that of other drugs such as opium or cannabis. Kratom...
Mitragyna speciosa Kratom use appears to be very safe in standard recreational doses. A person who consumes too much Mitragyna speciosa Kratom will experience strong nausea and vomit the consumed Kratom...
As previously mentioned, despite Mitragyna speciosa Kratom’s relatively long history of human use, Kratom and Kratom use has rarely been studied extensively, even in countries where Kratom use is...
Selected bibliography on Mitragyna speciosa Kratom and Kratom alkaloids Amattayakul T., The kraton leaves. J. Department of Medical Sciences, Thailand, vol. 2: 2, 104-108, 1960. Atthakor P. "Role Seen For...
In South-East Asia, and Thailand in particular, Mitragyna speciosa Kratom is most often chewed fresh, in whole leaf form, usually after removing the leaves’ central vein, which helps chewing and is said to...
The following common forms and preparations of “true” Mitragyna speciosa Kratom can be distinguished: Leaf form Kratom Traditional Kratom users of Thailand and Malaysia distinguish between different types...
The Mitragyna speciosa Kratom tree grows naturally throughout Southeast Asia, yet little is known of its traditional consumption outside of Thailand, Malaysia, Myanmar/Burma, countries which have mentioned...
The concept of "drug tolerance”, refers to the gradual decrease of a subject’s reaction and sensitivity to a psychoactive substance or drug, implying that progressively larger doses are required to achieve...
This is a very simple and efficient way of consuming Mitragyna speciosa Kratom. The simplest way would be the “toss and wash”, placing the Kratom leaf or Kratom leaf powder in a glass of water, stirring and...
The term Kratom refers to the Mitragyna speciosa tree, but also mainly to this tree’s leaves when used as a psychoactive or medicine, and their derived products such as crude extracts. The most common...
What is clear is that Mitragyna speciosa Kratom is not recommended for daily use. While such a practice is not nearly as problematic or dangerous as it would be with opiate or opioid use, it is clear that...
Mitragyna speciosa Kratom has been used as a medicine and as a recreational psychoactive for a long time in South-East Asia, and is therefore known to be relatively safe. Yet it is important to note that...
There are multiple ways to prepare Mitragyna speciosa Kratom, from making a simple tea with the leaves, leaf powder or extract, to more complex preparations, such as “Kratom cooking”. More than the novelty...
Mitragyna speciosa Kratom is illegal in many South-East Asian countries, such as Thailand, Malaysia, Myanmar (Burma) and Vietnam (though the specificities of the law is unclear). Kratom use is, however...
As previously explained in the section “Pharmacology and mode of action of Mitragyna speciosa Kratom” as well as in the “Potential applications and modern uses of Mitragyna speciosa Kratom” section,...
The term “narcotic” is based on the Greek word “narcosis”, the term used by Hippocrates for the process of benumbing, benumbed or sedated state. A “narcotic” substance refers to agents that benumb or...
The term “sedative”, or “sedative-hypnotic” refers to a class of substances that depress the central nervous system (C.N.S.), which induces a state of calmness, relaxation, reduction of anxiety, sleepiness,...
Mitragyna speciosa leaves, with their complex and rich chemical makeup, could easily have various practical applications in modern medicine, or become source of new and useful chemicals, which could be...
Mitragyna speciosa Kratom use is legal in most parts of the world, and is not specifically tested for in drug-screens or drug tests. Yet Kratom users facing potential drug-tests, such as urine drug-screens,...
The vernacular term Kratom refers to the Mitragyna speciosa var. Korthals tree and the products derived from its leaves, which concentrate the plant’s active principles. The botanical classification of...
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